Kris De Boeck Selected Research

eluforsen

1/2020	Antisense oligonucleotide eluforsen is safe and improves respiratory symptoms in F508DEL cystic fibrosis.
1/2019	Antisense oligonucleotide eluforsen improves CFTR function in F508del cystic fibrosis.

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Kris De Boeck Research Topics

Disease

35	Cystic Fibrosis (Mucoviscidosis) 11/2021 - 11/2003
7	Infections 01/2017 - 05/2005
4	Inflammation (Inflammations) 07/2021 - 07/2003
4	Asthma (Bronchial Asthma) 06/2011 - 10/2003
3	Ciliary Motility Disorders (Primary Ciliary Dyskinesia) 01/2017 - 05/2014
2	Dysbiosis 03/2016 - 11/2011
2	Exocrine Pancreatic Insufficiency 03/2016 - 11/2003
2	Fever (Fevers) 10/2014 - 08/2003
1	Reinfection 01/2020
1	Allergic Bronchopulmonary Aspergillosis 01/2018
1	Eosinophilia 01/2018
1	Male Infertility (Male Sterility) 01/2017
1	Chronic Mucocutaneous Candidiasis 11/2014
1	Empyema 10/2014
1	Inborn Genetic Diseases (Disease, Hereditary) 07/2014
1	Acute Kidney Injury (Acute Renal Failure) 07/2014
1	Bronchiectasis 02/2013
1	Granuloma 10/2011
1	Persistent Infection 12/2010
1	Lung Diseases (Lung Disease) 12/2010
1	Type 1 Hyper-IgM Immunodeficiency Syndrome 04/2007
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2007
1	Pneumococcal Infections 01/2007
1	IgA Deficiency 01/2007
1	Respiratory Tract Diseases (Respiratory Tract Disease) 11/2006
1	Hydrothorax 06/2006
1	Abdominal Pain (Pain, Abdominal) 04/2005
1	Pancreatitis 04/2005
1	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 08/2003
1	Lymphadenopathy 08/2003
1	Neutropenia 08/2003
1	Respiratory Sounds (Crackle) 07/2003

Drug/Important Bio-Agent (IBA)

6	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2021 - 02/2011
4	Proteins (Proteins, Gene)FDA Link 03/2016 - 12/2010
4	Anti-Bacterial Agents (Antibiotics)IBA 10/2014 - 02/2009
3	ChloridesIBA 11/2021 - 07/2014
3	ivacaftorIBA 12/2020 - 12/2014
3	Polysaccharides (Glycans)IBA 01/2020 - 01/2007
3	neodymium pyrocatechin disulfonate (NPD)IBA 05/2015 - 02/2011
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2014 - 07/2003
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 10/2013
2	eluforsenIBA 01/2020 - 01/2019
2	Antisense OligonucleotidesIBA 01/2020 - 01/2019
2	Pharmaceutical PreparationsIBA 12/2019 - 06/2011
2	lumacaftorIBA 01/2015 - 01/2012
2	Mannitol (Osmitrol)FDA LinkGeneric 07/2013 - 03/2012
2	Immunoglobulin M (IgM)IBA 01/2007 - 08/2003
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2007 - 09/2006
1	Transcription Factors (Transcription Factor)IBA 07/2021
1	Niclosamide FDA Link 07/2021
1	ivacaftor drug combination tezacaftorIBA 01/2021
1	AntibodiesIBA 01/2020
1	Immunoglobulin E (IgE)IBA 01/2018
1	Omalizumab (Xolair)FDA Link 01/2018
1	LigandsIBA 01/2017
1	Biocompatible Materials (Biomaterials)IBA 01/2017
1	SaltsIBA 01/2017
1	AnionsIBA 01/2017
1	STAT1 Transcription FactorIBA 11/2014
1	Glucose (Dextrose)FDA LinkGeneric 10/2014
1	CreatinineIBA 07/2014
1	Tobramycin (Nebcin)FDA LinkGeneric 07/2014
1	atalurenIBA 07/2014
1	Nonsense Codon (Nonsense Mutation)IBA 07/2014
1	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)FDA Link 12/2013
1	HeliumIBA 10/2013
1	Fatty Acids (Saturated Fatty Acids)IBA 05/2013
1	Chloride Channels (Chloride Channel)IBA 04/2013
1	PowdersIBA 03/2012
1	Interleukin-23 (Interleukin 23)IBA 12/2010
1	Interleukin-17 (Interleukin 17)IBA 12/2010
1	Interleukin-22 (IL-22)IBA 12/2010
1	Messenger RNA (mRNA)IBA 12/2010
1	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 02/2010
1	Amiloride (Midamor)FDA LinkGeneric 07/2009
1	Epithelial Sodium ChannelsIBA 07/2009
1	CD40 Ligand (CD40L)IBA 04/2007
1	Toll-Like Receptor 2IBA 01/2007
1	Immunoglobulin G (IgG)IBA 01/2007
1	Toll-Like Receptor 4IBA 01/2007
1	Fc gamma receptor IIAIBA 01/2007
1	Immunoglobulin A (IgA)IBA 01/2007
1	AllergensIBA 11/2006
1	Interleukin-12 (IL 12)IBA 11/2006
1	Formoterol Fumarate (Oxis)FDA Link 09/2006
1	Formoterol Fumarate Drug Combination Budesonide FDA Link 09/2006
1	Budesonide (Pulmicort)FDA LinkGeneric 09/2006
1	beta-DefensinsIBA 05/2005
1	Amylases FDA Link 04/2005
1	Lipase (Acid Lipase)FDA Link 04/2005
1	EnzymesIBA 11/2003
1	Proton Pump InhibitorsIBA 11/2003
1	Omeprazole (Prilosec)FDA LinkGeneric 11/2003
1	SteroidsIBA 08/2003

Therapy/Procedure

11	Therapeutics 01/2021 - 08/2003
1	Catheters 05/2015
1	Length of Stay 10/2014
1	Lung Transplantation 05/2013
1	Hematopoietic Stem Cell Transplantation 10/2011
1	Nebulizers and Vaporizers (Inhaler) 09/2006